Pathways of Hair Loss
Role of Transforming Growth Factor Beta-1
TGF-Beta 1 appears to inhibit the rate of hair follicle lengthening in vitro and in vivo in mice to promote the regression phase of the organ cultu...
How does hair follicle microinflammation cause hair loss?
Inflammation of the hair follicle, or folliculitis, can interfere with the normal growth of the hair and lead to hair loss. Folliculitis is ...
Expression of Insulin-Like Growth Factors
Of all the cytokines or growth factors that have been postulated to play a role in hair follicle, insulin-like growth factor- 1 (IGF-1) is known to...
Hair Follicle Cycling and Signaling Molecules
Hair growth is believed to be regulated by the interactive signals between the epithelial parts and mesenchymal-derived DP cells. Several cytokine...
Senescent Alopecia
A study comparing androgenetic alopecia and senescent alopecia using microarray analysis demonstrated significant differences in the gene express...
Perifollicular Fibrosis Management
On close histological observation of balded scalp biopsies, the miniaturization of terminal hairs is a distinguishing feature in AGA and is frequen...
How does dandruff cause hair loss?
Dandruff, also known as seborrheic dermatitis, is a common condition that causes the scalp to become flaky and itchy. It is not usually a se...
Oxidative Stress
The free radical theory of ageing as originally proposed by Harman as early as 1956 states that organisms/organs age because cells accumulate free ...
Insulin-Like Growth Factor (IGF-1)
IGF-1 is one of the important mechanisms contributing to male pattern baldness. Of all the cytokines or growth factors that have been postulated ...
What are the genetics of hair loss?
Why is AGA considered to be heritable?
The familial occurrence of AGA is well documented, and monozygotic twins display a striking phenotypic resem...
Blocking chronic inflammation of the hair follicle
Inflammation of the hair follicle, or folliculitis, can interfere with the hair growth cycle and lead to hair loss. Blocking inflammation in the h...
Boosting KI67 Expression, a cellular marker of proliferation
Boosting KI67 expression refers to increasing the amount of KI67 protein in cells. KI67 is a protein that is expressed in cells that are actively d...
